Ulcerative Colitis

Learn about Avail's Ulcerative Colitis Clinical Trials

Ulcerative colitis (UC) is a chronic disease that affects the colon. UC causes the lining of the large intestine to become inflamed. This inflammation leads to ulcers (tiny open sores) that secrete pus and mucus. It’s this unpleasant combination that causes intense discomfort and the frequent urge to empty one’s bowels.

This condition is an autoimmune disease, meaning that it’s caused by an abnormal immune response. In patients with ulcerative colitis, the immune system identifies food, bacteria, and other materials in the digestive tract as invading substances that could harm the body.

Woman experiencing effects of inflammation in her gut

The symptoms of ulcerative colitis can be very intense.

This case of mistaken identity is a very serious one. White blood cells are produced and sent into the lining of the intestines. This causes the chronic inflammation and ulcerations.

The research team at Avail Clinical Research is conducting ulcerative colitis clinical trials here in DeLand, Florida. They conduct research studies in order to develop a better understanding of UC and improve modern treatments for it. Would you be interested in participating in a ulcerative colitis clinical trial? Please fill out our form in the right hand of the page to apply online or call us at (386) 785-2400 to speak with a clinical trials expert.

Different Types of Inflammatory Bowel Disease

Please note that ulcerative colitis is different from the condition known as Crohn’s disease. They both produce similar symptoms, but there is a key difference. Crohn disease can affect any part of the gastrointestinal (GI) tract. Ulcerative colitis only impacts the colon and it’s relegated to the intestinal lining.

They are two types of inflammatory bowel disease (IBD), but this is not the same thing as irritable bowel syndrome (IBS). The later is a disorder that impacts the colon’s muscle contractions. Ulcerative colitis and other forms of IBD are characterized by intestinal inflammation, while IBS is not.

Who is at Risk for Ulcerative Colitis?

Despite the research that has been conducted, researchers still don’t know what causes the abnormal immune response. It’s likely that there are several factors involved, including:

  • Genetics
  • The immune system
  • Environmental factors such as antigens

Clinical studies suggest that ulcerative colitis could be caused by an interaction of a viral or bacterial infection within the colon and the body’s natural immune response.

Bacterial infection in the colon leads to ulcerative colitis

Researchers still don’t know for sure what causes this abnormal immune response.

You’ll experience some temporary inflammation as your immune system battles the infection. However, this will subside as you regain your health. It’s when UC has developed that the inflammation will be chronic.

Some Stats on Ulcerative Colitis

  • UC affects an estimated 700,000 Americans
  • Affects both men and women equally
  • Most patients diagnosed in their mid-30s
  • This disease can occur at any age
  • Studies show that 20 percent of UC patients have a close relative with UC

What is it like living with Ulcerative Colitis?

Ulcerative Colitis Complications

The possible complications of ulcerative colitis include:

  • A perforated colon (a hole in the colon)
  • Severe dehydration
  • Internal bleeding
  • Bone loss (osteoporosis)
  • Increased risk of colon cancer
  • Inflamed joints, eyes, and skin
  • Ulcers in the mouth
  • A rapidly swelling colon (known as a toxic megacolon)
  • Heightened risk of blood clots in the arteries and veins

(In some rare cases, it can lead to liver disease as well.)

Want to Enroll in an UC Clinical Trial in Florida?

Interested in participating in an ulcerative colitis clinical trial in DeLand? Our research team would love to talk with you about your eligibility for an upcoming study. It’s a big decision, so we’d be happy to answer any questions that you may have about participating in a clinical trial.

All study-related medical care and required treatments will be provided to participants free of charge. Plus, you may receive compensation for you time and any required travel. If you’d like to learn more, please give us a call at (386) 785-2400.

Ulcerative colitis is not the only medical condition that we are enrolling for at Avail Clinical Research. Our team is working hard to advance modern medicine and we could use your help. If you don’t have a medical condition and are otherwise healthy, you can still apply for enrollment in one of our healthy studies clinical trials. Help us solve tomorrow today!

Clinical Trial Indications