Acne Clinical Research

Acne is a mostly cosmetic issue, so it’s often overlooked by the general public. Unfortunately, some people develop more chronic cases of acne that are much harder to treat. We conduct acne clinical trials at our clinic in DeLand, because we’re looking to find better ways of treating and preventing acne for those in need. This skin condition can’t be managed effectively unless it’s well understood.

Woman treating her acne in Florida


Acne happens to be the most common skin condition in the country. The pimples and other blemishes occur as a result of hair follicles that get clogged with dead skin cells and oil. For this reason, acne can appear all over the body from your face down your back to your legs. Anyone who watches television has probably seen countless advertisements for various acne treatments, but this condition can be tricky to say the least.

Unsurprisingly, acne is much more common amongst teenagers as they are moving through puberty. However, clinical studies suggest that it’s becoming more prevalent amongst young children now too.

Acne is not a life-threatening condition, but it can cause a significant amount of emotional distress when symptoms are severe. Teenagers can struggle with low self esteem and other complications if they tend to have bad acne. Additionally, these pimples can leave lasting scars without proper treatment.

What Causes Acne?

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There are four primary factors which lead to acne breakouts:

  • Dead skin cells
  • Oil
  • Bacteria
  • Clogged pores

Most people who get acne have it on their face, neck, shoulders, chest and back. These are the parts of the body with the largest concentrations of sebaceous (oil-producing) glands. As mentioned earlier, pimples manifest when the hair follicles are clogged with dead skin cells and oil.

The hair follicles in the skin are connected to the oil glands. The glands produce sebum (an oily substance) that’s meant to lubricate the skin and hair. The sebum makes it way onto the skin’s surface by flowing along the hair shafts and through the follicles’ opening.

An excess amount of oil and dead skin can lead to clogging and buildup along the hair follicle. This plugged environment becomes a perfect breeding ground for bacteria. If the pore gets infected, then it also becomes inflamed.

The follicle wall may then bulge out which produces those whiteheads we all dread finding in the mirror. Some plugged follicles may open towards the surface and darken, creating what’s known as a blackhead. These resemble dirt that’s stuck in the pores, but are actually congested bacteria and oil which browns when exposed to the air.

A pimple is a raised red spot with a white center resulting from an infected follicle that has become inflamed. These blockages don’t always happen so close to the surface either. some that occur close to the root can produce a bump resembling a cyst underneath the skin’s surface. Acne usually doesn’t develop in the pores of the sweat glands.

Common Acne Triggers

The following factors are known to trigger outbreaks or worsen existing cases of acne:

  • Hormones – There’s a reason that teenagers tend to get more acne. During puberty, the level of androgens (a hormone) increases in girls and boys causing oil glands to enlarge and produce more oil. The hormonal fluctuations resulting from pregnancy and taking birth control can also impact oil production in the skin.
  • Medications – Specific medications like corticosteroids and lithium are known to exacerbate acne.
  • Diet – Research has shown that a diet high in carbohydrates and dairy products can trigger acne outbreaks. Unfortunately, chocolate also appears to be a factor. One important clinical study showed that the sweet treat increased acne in male participants who already had symptoms.
  • Stress Levels – High levels of stress in your everyday life can produce more acne.

Acne Myths and Misconceptions

We wanted to take this opportunity to dispel some of the common misconceptions surrounding acne:

  • Dirty Skin – Dirt does not produce acne. Ironically, washing too much or scrubbing your skin too hard can irritate the skin and produce more acne. You do want to stay clean, just make sure that you are gentle on your skin.
  • Greasy Foods – Here’s a popular acne misconception, but the truth is that eating greasy food has almost no effect on acne. The issue may come from spending a lot of time in an greasy environment where your skin is exposed to more oil.
  • Cosmetics – Makeup doesn’t necessarily cause acne, especially if you use ones that are oil-free and you don’t sleep in it. Remember that it’s the act of clogging the pores which will make things worse.

Acne Clinical Trials in DeLand, Florida

If you would like to take part in an acne clinical trial at our clinic, our experienced staff will be available to answer any of your questions and get you enrolled in the best study. Please note that if there is no link to the trial at the top of this page, then it means we aren’t enrolling for this skin condition.

For those who have never participated in a clinical trial before, we highly recommend spending some time in our study resource section. It has some extremely helpful information, such as good questions to ask your doctor before enrolling and our step-by-step guide to clinical participation.

Qualified participants will be compensated for time and travel, and any study related care. The following are all provided free of charge:

  • Physical examinations
  • Laboratory services
  • Study related medication

We are currently conducting clinical studies targeted towards a wide array of medical conditions at our state-of-the-art facility here in DeLand. You don’t have to be struggling with acne in order to qualify for one of our clinical trials. If you are interested in helping us advance modern medicine and save more lives, please give us a call today at (386) 785-2400.

Additional Resources on Acne

If you live near Central Florida, click here to learn more about participating in an acne clinical trial.

Clinical Trial Indications