Diabetic Nephropathy: Facts & Information

Learn about Avail's Diabetic Nephropathy Clinical Trial

Kidney damaged by diabetic nephropathyAre you familiar with diabetic nephropathy? We are conducting clinical trials for this medical condition and it’s important to know why. Without a doubt, more people are familiar with diabetes, but diabetic nephropathy is a related complication that is very serious. Our research team is working in collaboration with clinics around the country in order to help improve diagnostic tests and available therapies for diabetic nephropathy.

(Is this an opportunity that you are interested in? Please click on the link above or give us a call at (386) 785-2400.)

The term nephropathy refers to kidney damage or disease. Diabetic nephropathy is a condition that arises due to the damage diabetes has caused to the kidneys. It’s a serious complication that often leads to complete renal failure without serious medical attention. It is important to note that only some people with diabetes experience issues with their kidneys.

What Causes Diabetic Nephropathy?

The kidneys are vital organs responsible for filtering waste out of the blood. When diabetes is poorly managed, glucose levels can remain high for long periods of time. This will damage the essential blood vessels and the kidneys. It can cause renal impairment and eventually the kidneys may shut down completely (kidney failure).

Despite how much clinical researchers and medical experts have learned about diabetic nephropathy, it is still not clear why some diabetics experience this complication and others don’t.

What is known is that certain factors will put a diabetic’s kidneys at greater risk. The following are all risk factors for this medical condition:

  • High cholesterol
  • High blood pressure (hypertension)
  • Smoking cigarettes
  • Living with type 1 diabetes for an extended period of time (before the age of 20)
  • Ethnicity (studies show that Native Americans, African Americans, and Hispanics are at greater risk)

What Should You Know if You Have Diabetes?

There are no noticeable physical symptoms during the earliest stages of diabetic nephropathy. Diabetics are encouraged to go in for routine urinary analysis tests, as these are the best way to identify kidney damage at an early stage. Some cases can even be reversed before any permanent damage can take place.

If not, then it can take up to a decade for symptoms to manifest themselves. The condition may have progressed to a very advanced stage by that point. Typically, the earliest physical symptom of diabetic nephropathy is often swelling in the legs or feet.

Good news is that this complication can be diagnosed using a simple test that analyses urine for the presence of a protein called albumin. If this protein is present, it means that the kidneys are not functioning at 100 percent. We recommend scheduling this test annually if you have been diagnosed with diabetes.

The first line of treatment is usually medication that will help lower the blood pressure. This can prevent further damage as diabetic nephropathy does cause a rise in blood pressure. Patients will also experience a rise in cholesterol and triglyceride levels as well. Despite what we have learned in diabetic nephropathy clinical trials, it remains incredibly difficult to treat.

Although less common, doctors may need to ask patients to discontinue some medications they are taking for diabetes due to the damage they could cause to the kidneys in their weakened state. Diabetic nephropathy is a leading cause of sickness, hospitalization and death for people already living with diabetes. Without the proper medical attention early on, patients may soon require dialysis or even a kidney transplant to survive.

Interested in Enrolling in a Clinical Trial in DeLand, FL?

If you would like to volunteer for a diabetic nephropathy clinical trial, our dedicated team would love to answer any of your questions and get you enrolled in a study. Never participated in a clinical trial before? That’s no problem, but we do recommend that you spend some time looking through our study participant resource pages. This experience can be confusing at first, but these pages can help answer many of your questions.

Participants will be compensated for time and travel, and any study related care. The following are all provided free of charge:

  • Physical examinations
  • Laboratory services
  • Study related medication

We conduct clinical trials that target a wide range of medical conditions at our state-of-the-art facility here in DeLand. You don’t have to be living with a condition such as diabetic nephropathy in order to qualify for one. If you are interested in helping us advance modern medicine and save more lives, please give us a call today at (386) 785-2400.

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