Hepatic Impairment Clinical Research

Learn about Avail's Hepatic Impairment Clinical Trials

Liver failure starting in patientDo you know why hepatic impairment clinical research is so important? While  it is rare, this medical condition requires immediate treatment following a diagnosis.

This life-threatening condition can be reversed with proper treatment, but that’s not always the case. Our research team is working to improve available medications for this condition by conducting hepatic impairment clinical research in DeLand, Florida.

(Is this an opportunity that you are interested in? Please fill out the form in the right hand corner above or give us a call at (386) 785-2400.)

The liver can begin to fail when large portions of the vital organ is damaged beyond repair. This prevents the liver from functioning properly. While impairment can occur gradually over years, acute liver failure is a condition that can develop in as little as 3 days. These rare cases are very difficult to catch early on.

It’s more common for someone to develop chronic liver failure over a longer period of time.

What Causes Hepatic Impairment?

The type of liver failure you develop will differ depending on the exact cause. Chronic hepatic impairment can be caused by the following:

  • Hepatitis B
  • Hepatitis C
  • Cirrhosis
  • Hemochromatosis
  • Long-term malnutrition
  • Long-term alcohol consumption

(We have more information on hepatitis B and hepatitis C if you’d like to learn more about these infections.)

Common causes of acute hepatic failure (rapid liver failure) include:

  • Adverse reaction to prescription or herbal medications
  • Acetaminophen (Tylenol) overdose
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C (presents higher risk in children)
  • Eating poisonous mushrooms in the wild

Is Your Liver Healthy? Watch this Video!

Complications from Acute Liver Failure

A rapid loss of liver function can result in the following complications:

  • Cerebral Edema – This means excessive fluid has built up in the brain. The increased pressure can displace brain tissue producing a herniation. A severe cerebral edema could deprive the brain of oxygen.
  • Internal Bleeding – Hepatic impairment leads to blood that doesn’t clot as effectively. Acute liver failure often results in bleeding from the gastrointestinal tract. Also, a simple cut may become a persistent bleeder.
  • Infections – A failing liver puts you at greater risk for a variety of infections. Many patients come in with respiratory, urinary and blood infections.
  • Kidney Failure – Renal (kidney) failure often follows after the liver has begun to fail. It is particularly common when the cause is an acetaminophen overdose.

Preventing Hepatic (Liver) Impairment and Failure

What’s the best way to protect your liver function? Make sure that you don’t contract hepatitis or cirrhosis.

Doctor tells woman how to limit her risk of developing hepatitis C


Reduce your risk by taking these preventive steps:

  • Maintain a healthy diet that includes all major food groups
  • Get vaccinated for hepatitis A and B
  • Limit your alcohol consumption over the long run
  • Don’t take acetaminophen (especially Tylenol) with alcohol
  • Wash your hands regularly and thoroughly, especially before touching food and following a trip to the bathroom
  • Don’t directly handle blood
  • Don’t share your razor or toothbrush with anyone else
  • Take precautions if you plan on getting a piercing or tattoo (pick an establishment that is sanitary)
  • Practice safe sex
  • Don’t share any needles!

(Read this post for some more hepatitis prevention tips if you have a minute.)

Enroll in a Hepatic Impairment Clinical Trial in DeLand

Would you like to volunteer for a hepatic impairment clinical trial? Our research team is looking for real life superheroes like you!

We’re available to answer your questions and get you enrolled in one of our studies. Anyone who is unfamiliar with the clinical research process should spend some time in our participant resource section.

Qualified participants can receive compensation for their time and necessary travel. They’ll also receive the following free of charge:

  • Physical examinations
  • Laboratory services
  • Study related medication

Our team is conducting clinical trials for a wide range of medical conditions here in DeLand. This means that we likely have an enrolling study that you can qualify for, even if you don’t have hepatic impairment. If you are interested in helping us advance modern medicine and save more lives, please give us a call today at (386) 785-2400.

Some Additional Resources on Hepatic Impairment & Failure

Clinical Trial Indications