High Cholesterol

Learn about Avail's High Cholesterol Clinical Trials

Human artery affected by high cholesterolYou might be surprised to learn how many people are living with high cholesterol levels. Unfortunately, most people haven’t had their cholesterol levels tested and aren’t aware that they are at risk. This medical condition can be treated, but some people don’t respond well to this line of treatment. Clinical trials, like the ones we conduct here in DeLand, allow our staff to evaluate new therapies which could better aid people struggling to lower their cholesterol.

So what is cholesterol exactly? It’s the waxy substance that the body uses to construct resilient new cells– it’s very important. Cholesterol is transported through the bloodstream with lipids (fats). The body is able to create most of the cholesterol it requires on it’s own, but it will also absorb more from foods that are consumed. High levels of cholesterol can put you at risk for cardiovascular disease.

Unfortunately, you could be living with high cholesterol without even realizing it. This condition doesn’t produce many noticeable symptoms (at least on it’s own). However, lipid cells could start forming plaque (these fatty deposits) along the walls of the artery. This forces the heart to pump harder in order to circulate enough blood through the heart. This can lead to two major issues:

  • Oxygen-deprived blood that raises the risk of myocardial infarction (heart attack)
  • A brain that doesn’t get enough blood could suffer a loss of function (stroke)

Fast Facts on High Cholesterol

  • The human body doesn’t require any cholesterol from the diet
  • High cholesterol can be inherited
  • Children can develop high cholesterol
  • Women’s cholesterol levels tend to rise after menopause
  • Uncommonly low cholesterol levels can also put you at risk

Studies have shown us that a propensity towards developing high cholesterol can be inherited. Still, it’s far more likely that unhealthy lifestyle habits are the real source of the problem. This is good news because it means that most cases can be treated and future cases can be prevented. An improved overall diet combined with regular physical fitness can work wonders for the body. There are also some medications which have been designed to reduce cholesterol.

Different Types of Cholesterol

The human body uses cholesterol for a variety of purposes, which means that it’s required in many different locations. So the waxy substance gets attached to these proteins and transported through the bloodstream. The combination of cholesterol and protein is called a lipoprotein. These lipoprotein don’t all carry the same type of cholesterol. There are different classifications known as:

  • Low-Density Lipoprotein (LDL) – This is referred to as “bad” cholesterol, since it tends to form the majority of plaque that can obstruct and harden the arteries.
  • Very-Low-Density Lipoprotein (VLDL) – This carries the largest concentration of fat cells (triglycerides) and contributes to the overall size of LDL cholesterol.
  • High-Density Lipoprotein (HDL) – Also referred to as “good” cholesterol, HDL cleans of leftover cholesterol particles and transports them back to the liver.

There are a variety of factors which people may have no control over, but still contribute to overall cholesterol levels. There’s isn’t anything that we can change about genetics. However, most people have high cholesterol as a result of a poor diet (one that is high in saturated fats for example) and not staying active. Leading studies have shown just how beneficial exercise and diet can be.

(Check of this list of healthy food options before your next trip to the grocery store.)

You should understand that participating in a clinical trial here in DeLand is not a uniform type of experience. Participating in a high cholesterol research study at Avail Clinical Research may not involve more than granting our research team access to copies of specific test results. It all depends of the specific protocol for a new clinical trial.

Qualified participants can receive compensation for time and travel expenses, as well as for any other trial related care. The following are provided for all accepted applicants:

  • Physical examinations
  • Laboratory services
  • Study related medication

High Cholesterol Clinical Trials in DeLand, FL

Avail Clinical Research is currently conducting a wide array of clinical studies targeted towards certain conditions. You may be eligible to participate in one of our high cholesterol clinical trials and to contribute to the development and approval of a new drug or treatment. As a participant, there is no cost to you at any point during the study and health insurance is not required. Browse our clinical trials being conducted now to find the study best suited for you.

An Animated Video on High Cholesterol

Resources for High Cholesterol

Cholesterol Management Center – WebMD

American Heart Association

National Cholesterol Education Program

Mayo Clinic

If you live near Central Florida, click here to learn more about participating in a high cholesterol clinical trial. Also, our sister site Achieve Clinical Research conducts high cholesterol clinical trials in Birmingham, Alabama.


Clinical Trial Indications