Rheumatoid Arthritis (RA)

Learn about Avail's Rheumatoid Arthritis Clinical Trials

Doctor examining hands affected by rheumatoid arthritisDo you know why rheumatoid arthritis is the focus of many clinical trials? There is currently no cure available for people who’ve been diagnosed with this chronic inflammatory condition. Clinical research trials, like the ones we conduct here in DeLand, serve as a viable alternative for people who haven’t had much success with the treatments currently available for RA.

Rheumatoid arthritis is a chronic inflammatory condition which affects people of every age. Studies have shown that RA is the most common form of juvenile arthritis. Long-term inflammation from this disease can cause permanent damage to the joints. This chronic condition is also progressive, meaning the symptoms of RA will get steadily worse if not properly treated.

We are currently testing new medications and therapies in clinical trials which have provided further insight into the biology of rheumatoid arthritis. We would also like to improve our ability to reduce the adverse effects of many contemporary RA medications like methotrexate (MTX). This one in particular has acquired some notoriety for its reported side effects.

Rheumatoid Arthritis Fast Facts

  • Smoking can trigger rheumatoid arthritis
  • More than 1.3 million Americans are living with RA
  • Rheumatoid arthritis can lead to permanent disability and even death
  • Rheumatoid arthritis is an autoimmune disease
  • Rheumatoid arthritis is an active area of medical research

Did you know that much of what we now know about rheumatoid arthritis is thanks to a special woman who herself was afflicted with the disease? Dorothy Hodgkin was diagnosed with a severe form of RA in her late twenties. This inspired her to devote her life to medicine, and she was able to develop X-ray crystallography which provided doctors with an unprecedented glimpse at the effects of this disease.

RA is a type of Autoimmune Disease

It should be noted that rheumatoid arthritis is actually an autoimmune disease. This type of affliction is caused when the patient’s immune system begins attacking the body’s own healthy tissues. This in turn produces chronic symptoms like inflammation and pain in the affected joints. This also means that the symptoms of the disease can negatively impact vital organs as well. RA patients also must contend with symptoms that come and go in episodic periods.

People who’ve been diagnosed with rheumatoid arthritis can experience inflammation in any joint of their body. That being said, clinical studies have shown that most early symptoms develop in the small joints of the fingers or toes. Late-stage RA is much more likely to be in the larger joints. Its also quite common for the symptoms to affect the corresponding joint on both sides of the body (this is called mirroring).

This autoimmune disorder may develop at any age, but most people are diagnosed with RA after they’ve turned 40. Additionally, it would seem that rheumatoid arthritis affects more women than men overall.

What Causes Rheumatoid Arthritis

The exact cause of rheumatoid arthritis remains unknown, but experts believe that genetics play a major role. Although a person’s genetics may not be the trigger, it would seem that it can make them much more susceptible to particular external factors. Some theorize that the autoimmune response could even be triggered by a viral or bacterial infection.

You should understand that participating in a clinical trial here in DeLand does not have to be a demanding experience. Participating in a rheumatoid arthritis research study at Avail Clinical Research may only require agreeing to let our researchers have a copy of your test results. but most will require a little more involvement.

Qualified participants can receive compensation for time and travel expenses, as well as for any other trial related care. The following are provided for all accepted applicants:

  • Physical examinations
  • Laboratory services
  • Study related medication

Rheumatoid Arthritis Clinical Trials

Avail Clinical Research is currently conducting a wide array of clinical studies targeted towards certain conditions. You may be eligible to participate in one of our rheumatoid arthritis clinical trials and contribute to the development and approval of a new drug or treatment. As a participant, there is no cost to you at any point during the study and health insurance is not required. Browse our clinical trials being conducted now to find the study best suited for you.

See If You Qualify for Our New Clinical Trial

Resources for Rheumatoid Arthritis (RA)

American College of Rheumatology

Arthritis Foundation

National Rheumatoid Arthritis Society

Rheumatology Research Foundation

If you live near Central Florida, click here to learn more about participating in a RA clinical trial. Also, our sister site Achieve Clinical Research conducts RA clinical trials in Birmingham, Alabama.


Clinical Trial Indications